Netspot ga68 generator#

Use 1 mL low dead space plastic syringe to precisely measure the adequate volume of reaction buffer to be added during preparation. Radiolabeling of carrier molecules with gallium (Ga 68) chloride is very sensitive to the presence of trace metal impurities. Use non-metallic or silicone coated needles to minimize trace metal impurity levels. Prepare syringes for elution and reconstitution steps per Table 1 below. Set the temperature of the shielded dry bath to 95☌ (203☏), and wait for the temperature to reach the set point and stabilize.Į. Ge 68 breakthrough and other gamma emitting radionuclides should be ≤ 0.001%. Test periodically (weekly) the Ga 68 chloride eluate for Ge 68 breakthrough by suitable method. Use suitable shielding to reduce radiation exposure.Ĭ. Prepare Ga 68 dotatate for intravenous injection according to the following aseptic procedure:Ī.

Ancillary supplies needed (not supplied in kit): 1 mL sterile plastic syringe, 5 mL sterile plastic syringe, non-metallic or silicone coated sterile needles, 0.2 micron sterile vented filter. Ancillary supplies (not included in the kit): Vial 2 (buffer vial) contains: 60 mg formic acid 56.5 mg sodium hydroxide and water for injection.Vial 1 (reaction vial with lyophilized powder) contains: 40 mcg dotatate, 5 mcg 1,10-phenanthroline 6 mcg gentisic acid 20 mg mannitol.The Ge 68/Ga 68 generators are not supplied with the NETSPOT kit.

Netspot ga68 generator#

IRE ELiT Galli Eo Germanium 68/Gallium 68 (Ge 68/Ga 68) generator.Eckert & Ziegler GalliaPharm Germanium 68/Gallium 68 (Ge 68/Ga 68) generator.The NETSPOT kit is supplied as 2 vials which allows for direct preparation of Ga 68 dotatate injection with the eluate from one of the following generators (see below for specific instructions for use with each generator):